… reported a randomized placebo-controlled trial, the Qure study, … therapy (CBT), and not
doxycycline, was significantly more effective than placebo in reducing fatigue severity in Q fever …

… registry on 18 March 2011 as a randomised controlled trial. … long-term treatment with
doxycycline or cognitive behavioral … of long-term doxycycline use, we still recommend CBT as …

… of a randomized controlled trial that investigated the efficacy of … long-term doxycycline treatment
with a placebo on fatigue … the Qure study, doxycycline was not more effective in reducing …

… and cognitive-behavioral therapy on fatigue severity in patients with … Long-term effect
of cognitive behavioural therapy and doxycycline treatment for patients with Q fever fatigue …

… as a single control group, since doxycycline did not significantly reduce … Effectiveness of
cognitive behavioral therapy for the … to cognitive behavioural therapy in Q fever fatigue syndrome …

… , as this study focused on the long term impact of sequelae of Q fever. Patients were invited
for … , however there were no differences in fatigue severity and psychological distress [39]. …

… previous research that concluded that long-term doxycycline use did … Effectiveness of
Long-term Doxycycline Treatment and CognitiveBehavioral Therapy on Fatigue Severity in Patients …

… Long-term outcomes of CBT for severe fatigue have been mixed: some studies have shown
sustainment of treatment … Fatigue severity was assessed with the fatigue subscale of the 20-…

… Q Fever Fatigue Syndrome (Qure) study found that long-term doxycycline treatment did not
reduce Q fever fatigue syndrome, whereas the use of cognitive behavioral therapy (CBT) was …

… is effective in reducing fatigue severity following COVID-19, this intervention could contribute
to alleviating the long-term … one of its most prevalent and distressing long-term symptoms. …